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Ruthenium and Osmium Complexes in Cancer Research by Maria Rita is a document available to read on EtoBox.
This study investigates novel ruthenium and osmium complexes with quinoxalinone ligands for their antiproliferative effects on human cancer cell lines. The synthesized complexes were characterized using various spectroscopic techniques, and their cytotoxicity was assessed, revealing IC50 values ranging from 0.3 to 140 μM. The results indicate that osmium complexes generally exhibit a more consistent increase in cytotoxicity compared to ruthenium complexes, with some compounds inducing apoptosis in cancer ce
- Author
- Maria Rita
- Language
- EN