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Hepatocellular Carcinoma During Pregnancy and Its Comparison with Other Pregnancy-associated Malignancies by W. Y. Lau; W. T. Leung; S. Ho; S. K. Lam; C. Y. Li; P. J. Johnson; R. Williams; A. K. C. Li is a Medicine article available to read on EtoBox.
What is Hepatocellular Carcinoma During Pregnancy and Its Comparison with Other Pregnancy-associated Malignancies about?
Background. Cancer in pregnancy is rare and hepatocellular carcinoma (HCC) in pregnancy even rarer. The impact of pregnancy on the prognosis of patients with different types of cancer remains controversial. Reported cases of HCC in pregnancy are largely isolated and highly scattered. Thus, the effect of pregnancy on the prognosis of patients with HCC and the risk factors of developing HCC in pregnancy are not well documented. Methods. A series of five patients with HCC in pregnancy seen at two different centers is reported. A Medlar search for articles between 1957 and 1993 with the key words "Hepatocellular Carcinoma" and "Pregnancy" was conducted. All reported cases were combined and analyzed in terms of race, age, parity, hepatitis B surface antigen status, cirrhosis, serum alpha-fetoprotein (AFP) levels at presentation, history of taking oral contraceptive pills and fetal and maternal outcome. The impact of pregnancy on 12 other malignancies as reported in the medical literature also was reviewed. Results. To the authors' knowledge, The five cases reported here constitute the largest series of HCC in pregnancy. A literature search revealed 23 additional cases. Analysis of the 2
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It is typically read by researchers, students, and practitioners in Medicine.
- Author
- W. Y. Lau; W. T. Leung; S. Ho; S. K. Lam; C. Y. Li; P. J. Johnson; R. Williams; A. K. C. Li
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)
- Published
- 1995
- Language
- EN
- Field
- Medicine (Health Sciences)