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Physicians' preference values for hepatitis C health states and antiviral therapy: A survey by Raj Patil; Scott J Cotler; Geraldine Banaad-Omiotek; Robert A McNutt; Michael D Brown; Sheldon Cotler; Donald M Jensen is a Medicine article available to read on EtoBox.
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Background: Physicians' perspectives regarding hepatitis C shape their approach to patient management. We used utility analysis to evaluate physicians' perceptions of hepatitis C-related health states (HS) and their threshold to recommend treatment. ## Methods: A written questionnaire was administered to practicing physicians. They were asked to rate hepatitis C health states on a visual analog scale ranging from 0% (death) to 100% (health without hepatitis C). Physicians then judged quality of life associated with the side effects of antiviral therapy for hepatitis C and indicated the sustained virological response rate that they would require to recommend treatment. Results: One hundred and thirteen physicians from five states were included. Median utility ratings for hepatitis C health states declined significantly with increasing severity of symptoms: HS1-No Symptoms, No Cirrhosis (88%; 12% reduction from good health), HS2-Mild Symptoms, No Cirrhosis (66%), HS3-Moderate Symptoms, No Cirrhosis (49%), HS4-Mild Symptoms, Cirrhosis (40%), HS5-Severe Symptoms, Cirrhosis (18%) [p < 0.001]. The median rating for life with side effects of antiviral therapy was 47%, suggesting a 53% red
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- Author
- Raj Patil; Scott J Cotler; Geraldine Banaad-Omiotek; Robert A McNutt; Michael D Brown; Sheldon Cotler; Donald M Jensen
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2001-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1471-230X)
- Published
- 2001
- Language
- EN
- Field
- Medicine (Health Sciences)