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PmrI Gene and Polymyxin B Resistance by kanismian is a document available to read on EtoBox.
The study identifies the PpmrI gene in Proteus mirabilis, which is essential for resistance to polymyxin B, biofilm formation, and urothelial cell invasion. The gene is regulated by RppA, a response regulator that mediates PpmrI expression in response to polymyxin B exposure. These findings provide insights into the mechanisms of antibiotic resistance and virulence in P. mirabilis.
- Author
- kanismian
- Language
- EN