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The antihuman globulin test (AHG) detects antibodies or complement bound to red blood cells. It was originally developed in 1908 and further advanced in 1945-1946. The AHG test uses polyspecific or monospecific reagents containing anti-IgG and/or anti-C3d to detect IgG, C3d or both on red blood cells. The direct AHG test detects in vivo sensitization as seen in hemolytic diseases and transfusion reactions, while the indirect test detects atypical antibodies in serum. Positive AHG tests help diagnose various

Author

ISABELLA MARIE CABURNAY

Language

EN