Can I read SPNS2 Exports Sphingosine-1-Phosphate and Imports Glucose: Article on EtoBox?

SPNS2 Exports Sphingosine-1-Phosphate and Imports Glucose: Article by Prasun Pradhan is a document available to read on EtoBox.

What is SPNS2 Exports Sphingosine-1-Phosphate and Imports Glucose: Article about?

The study investigates the role of Spinster homolog 2 (SPNS2) in the transport of sphingosine-1-phosphate (S1P) and glucose, revealing that SPNS2 functions as an antiporter, exporting S1P while importing glucose. The research demonstrates that SPNS2 directly binds glucose and identifies key amino acids involved in this process, linking SPNS2 to glucose homeostasis with significant implications for metabolic diseases. Deletion of SPNS2 in mice leads to dysglycemia, emphasizing its critical role in regulating

Author

Prasun Pradhan

Language

EN