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Anthocyanin compositions and biological activities from the red petals of Korean edible rose (Rosa hybrida cv. Noblered) by Jin Hwan Lee; Hyeon-Jin Lee; Myoung-Gun Choung is a Agricultural and Biological Sciences article available to read on EtoBox.

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The objectives of the present study were to investigate anthocyanin profiles and their biological properties, including antioxidant, anticancer, and antiallergic, from the red petals of Korean edible rose (Rosa hybrida cv. Noblered). The acidic methanol extract of this species showed potent biological activities at a concentration of 50 lg/mL. Its anthocyanins were characterised as cyanidin 3,5-di-O-glucoside and pelargonidin 3,5-di-O-glucoside using reversed-phase C 18 column chromatography, NMR spectroscopy, and HPLC-DAD-ESI/MS analysis. Cyanidin 3,5-di-O-glucoside was the predominant constituent (375 mg/100 g), representing about 85% of total content. Cyanidin 3,5-di-O-glucoside exhibited good scavenging activity against DPPH radical with IC 50 value of 55.2 lg/mL; pelargonidin 3,5-di-O-glucoside showed potent anticancer effects against LNCap (human prostate cell line), ACHN (human renal cell line) and MOLT-4F (human leukaemia cell line) cell cultures, with IC 50 values of 6.43, 18.3, and 6.78 lg/mL, respectively. Antiallergic activities were only moderate.

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Author

Jin Hwan Lee; Hyeon-Jin Lee; Myoung-Gun Choung

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0308-8146)

Published

2011

Language

EN

Field

Agricultural and Biological Sciences (Life Sciences)