Can I read Patient-Derived Xenograft Models of Human Cancer on EtoBox?

Patient-Derived Xenograft Models of Human Cancer by Yuzhuo Wang,Dong Lin,Peter W. Gout (eds.) is a nonfiction available to read on EtoBox.

What is Patient-Derived Xenograft Models of Human Cancer about?

Preface 6 Contents 8 List of Contributors 10 1: Patient-Derived Tumor Xenografts: Historical Background 13 A Point on Terminology 13 A Brief Historical Context 14 Early Attempts 14 Establishing PDX Cancer Models Using Immune-Deficient Mice 17 References 18 2: Towards Best Practice in Establishing Patient-Derived Xenografts 22 Introduction 23 Primary Versus Serially Transplantable PDXs 24 Methods for Generating Patient-Derived Xenografts 25 Sources of Tissue for Patient-Derived Xenografts 25 Non-Malignant Tissue 25 Localised Tumour Tissue 26 Metastatic Tumour Tissue 26 Circulating Tumour Cells 27 Sorted or Cultured Cancer Cells 28 Preparation of Fresh Tissue for Xenografting 28 Influence of the Mouse Host on Patient-Derived Xenografts 29 Systemic Features of the Mouse Host: Strains and Steroids 29 Local Features of the Mouse Host: Graft Site 30 Authentication of Patient-Derived Xenografts 31 Summary and Conclusions 32 References 32 3: Fidelity and Stability of PDX Models 40 Introduction 40 The Fidelity of PDX Models 41 Fidelity in Histopathology 42 Fidelity in Molecular Features 43 Fidelity in Stroma/Microenvironment 44 Fidelity in Tumor Heterogeneity 44 Fidelity in Response and Res

Who reads Patient-Derived Xenograft Models of Human Cancer?

Author

Yuzhuo Wang,Dong Lin,Peter W. Gout (eds.)

Publisher

Humana

Published

2017

Language

EN

Category

nonfiction