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Can I read Selection of a Polyurethane Membrane for the Manufacture of Ventricles for a Totally Implantable Artificial Heart: Blood Compatibility and Biocompatibility Studies on EtoBox?
Selection of a Polyurethane Membrane for the Manufacture of Ventricles for a Totally Implantable Artificial Heart: Blood Compatibility and Biocompatibility Studies by Marie-Claire Bélanger; Yves Marois; Raynald Roy; Yahye Mehri; Eric Wagner; Ze Zhang; Martin W. King; Mingjing Yang; Charles Hahn; Robert Guidoin is a Medicine article available to read on EtoBox.
What is Selection of a Polyurethane Membrane for the Manufacture of Ventricles for a Totally Implantable Artificial Heart: Blood Compatibility and Biocompatibility Studies about?
**Abstract:** Membranes made from 4 commercial poly(carbonate urethanes): Carbothane (CB), Chronoflex (CF), Corethane 80A (CT80), and Corethane 55D (CT55), and from 2 poly(ether urethanes): Tecoflex (TF) and Tecothane (TT) were prepared by solution casting and sterilized by either ethylene oxide (EO) or gamma radiation. Their biocompatibility was evaluated in vitro in terms of proliferation, cell viability, and adhesion characteristics of human umbilical veins (HUVEC), monocytes (THP‐1), and skin fibroblasts, and by measuring complement activation through the generation of the C3a complex. Their hemocompatibility was determined by measuring the level of radiolabeled platelet, neutrophil, and fibrin adhesion in an ex vivo arteriovenous circuit study in piglets as well as via an in vitro hemolysis test. The results of this study showed no endothelial cell proliferation on any of the materials. The cell viability study revealed that the CB, CF, and TF membranes sterilized by EO maintained the highest percentage of monocyte viability after 72 h of incubation (>70%) while none of the gamma‐sterilized membranes displayed any cell viability. The fibroblast adhesion and C3a generation assa
Who reads Selection of a Polyurethane Membrane for the Manufacture of Ventricles for a Totally Implantable Artificial Heart: Blood Compatibility and Biocompatibility Studies?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Marie-Claire Bélanger; Yves Marois; Raynald Roy; Yahye Mehri; Eric Wagner; Ze Zhang; Martin W. King; Mingjing Yang; Charles Hahn; Robert Guidoin
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0160-564X)
- Published
- 2000
- Language
- EN
- Field
- Medicine (Health Sciences)