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Effect of Tricyanoaminopropene on the Amnesic Effect of Electroconvulsive Shock by Walter B. Essman is a Neuroscience article available to read on EtoBox.

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Several previous studies have indicated that the consolidation of the memory trace may be temporally defined in terms of the degree to which post-learning electroeonvulsive shock (ECS) results in a retrograde retention deficit for the previously initiated behavior (DuNcAN, 1949; HERIOT and COT,S,~AN, 1962). Several hypotheses have been generated regarding the effect of ECS in relation to memory formation. One of these is the suggestion that those agents or events which result in an experimentally induced retrograde amnesia exert their effects through an alteration in the activity and/or concentration of central nervous system nucleic acids (Ess~AN, 1965). This suggestion has found some indirect support in a study by MIEAILOVICg et al. (1958) in which it was reported that a single ECS in cats resulted in a 20--25~ reduction in brain ribonucleic acid (I~NA). Although this observation does not necessarily explain the relationship between ECS and retrograde amnesia, or between nucleic acids and memory, it is consistent with earlier work which has shown that an intracellular loss of RNA followed insulin-induced convulsions (HYDg~, 1944) and electrical stimulation of spinal ganglion cell

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Author

Walter B. Essman

Publisher

Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 0033-3158)

Published

1966

Language

EN

Field

Neuroscience (Life Sciences)