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Early PET imaging with [68]Ga-PSMA-11 increases the detection rate of local recurrence in prostate cancer patients with biochemical recurrence by Christian Uprimny; Alexander Stephan Kroiss; Josef Fritz; Clemens Decristoforo; Dorota Kendler; Elisabeth von Guggenberg; Bernhard Nilica; Johanna Maffey-Steffan; Gianpaolo di Santo; Jasmin Bektic; Wolfgang Horninger; Irene Johanna Virgolini is a Medicine article available to read on EtoBox.

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## Purpose: Pet/ct using ga-labelled prostate-specific membrane antigen psma-11 (hbedd-cc) has emerged as a promising imaging method in the diagnostic evaluation of prostate cancer (pc) patients with biochemical recurrence. however, assessment of local recurrence (lr) may be limited by intense physiologic tracer accumulation in the urinary bladder on whole-body scans, normally conducted 60 min post-tracer injection (p.i.). it could be shown on early dynamic imaging studies that ga-psma-11 uptake in pc lesions occurs earlier than tracer accumulation in the urinary bladder. this study aims to investigate whether early static pet acquisition increases detection rate of local recurrence on ga-psma-11 pet/ct in comparison to pet imaging 60 min p.i.. ## Methods: 203 consecutive pc patients with biochemical failure referred to ga-psma-11 pet/ct were analysed retrospectively (median prostate specific antigen (psa) value: 1.44 ng/ml). in addition to whole-body pet/ct scans 60 min p.i., early static imaging of the pelvis was performed, starting at a median time of 283 s p.i. (range: 243-491 s). assessment was based on visual analysis and calculation of maximum standardized uptake value (suv)

Who reads Early PET imaging with [68]Ga-PSMA-11 increases the detection rate of local recurrence in prostate cancer patients with biochemical recurrence?

Author

Christian Uprimny; Alexander Stephan Kroiss; Josef Fritz; Clemens Decristoforo; Dorota Kendler; Elisabeth von Guggenberg; Bernhard Nilica; Johanna Maffey-Steffan; Gianpaolo di Santo; Jasmin Bektic; Wolfgang Horninger; Irene Johanna Virgolini

Publisher

Springer Science and Business Media LLC

Published

2017

Language

EN

Field

Medicine (Health Sciences)