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TREM2 Defends The Liver Against HCC by parkhyunjin0813 is a document available to read on EtoBox.
The study investigates the role of TREM-2 in hepatocellular carcinoma (HCC), revealing that TREM-2 expression is upregulated in HCC tissues and is protective against liver tumor development. Mice lacking TREM-2 exhibited increased liver damage, inflammation, and tumor burden, suggesting that TREM-2 plays a multifactorial protective role in hepatocarcinogenesis. The findings indicate that TREM-2 agonism may be a potential therapeutic strategy in managing HCC, although careful evaluation of its effects is nec
- Author
- parkhyunjin0813
- Language
- EN