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Liver Slices for Drug Interaction Research by adrian lifschitz is a document available to read on EtoBox.
This study investigates the use of precision-cut liver slices (PCLS) from cattle to assess metabolic drug-drug interactions, specifically between the anthelmintic albendazole (ABZ) and the flavin-monooxygenase inhibitor methimazole (MTZ). The research validates the production and culture techniques of bovine PCLS, demonstrating their viability and functionality over a 12-hour incubation period. Results indicate that PCLS are a reliable tool for studying metabolic interactions in bovine species, with signifi
- Author
- adrian lifschitz
- Language
- EN