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What is Discovery and Evaluation of Novel Sulfonamide Deri about?

This article discusses the discovery and evaluation of novel sulfonamide derivatives targeting aromatase in estrogen-receptor-positive breast cancer. The synthesized compounds demonstrated significant aromatase inhibition and cytotoxicity, with compounds 3 and 9 showing promising potency and selectivity against cancer cells. Additionally, potential multi-target therapeutic strategies were identified, highlighting the need for further development of these compounds to improve treatment outcomes.

Author

silvia.tarazona02

Language

EN