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The document discusses antihypertensive agents, specifically angiotensin receptor blockers such as Irbesartin and Losartin, which work by blocking Angiotensin I to regulate blood pressure and fluid balance. It outlines their adverse effects, including hyperkalaemia and foetal toxicity, and their use as alternatives to ACE inhibitors in treating hypertension. Additionally, it details the structure-activity relationships of these agents, emphasizing the importance of specific chemical groups for optimal activ
- Author
- Ali Sabir
- Language
- EN