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Auxological, Clinical and MRI Findings in Taiwanese Children with Growth Hormone Deficiency by F.-S. Lo; L.-Y. Chang; M.-H. Yang; Y.-H. Van; Y.-Y. Wai is a Medicine article available to read on EtoBox.

What is Auxological, Clinical and MRI Findings in Taiwanese Children with Growth Hormone Deficiency about?

Growth hormone deficiency (GHD) may be classified into partial isolated GHD (partial IGHD), severe IGHD or multiple pituitary hormone deficiency (MPHD) by the severity of GHD or associated with deficiency of one or more other anterior pituitary hormones during provocative tests. Morphological alterations on magnetic resonance imaging (MRI) in patients with GHD include pituitary hypoplasia, absence or interruption of pituitary stalk, and absence or ectopic posterior lobe. This study investigated the auxological, clinical severity, and anatomical characteristics of the pituitary hypothalamic region by MRI and correlated their relationships. We evaluated these parameters in 45 Taiwanese children with GHD (31 males and 14 females), aged from 3.13 to 17.91 years (10.5 ± 2.5), who were divided into diagnostic subgroups of partial IGHD (18 patients), severe IGHD (13 patients), and MPHD (14 patients). We found that BA-CA, peak GH, IGF-I, IGF-I SDS, and height SDS were significantly different among these three groups. The partial IGHD group had significantly higher IGF-I than the MPHD group. There was no significant difference in prematurity, cesarean delivery, birth order, neonatal jaundic

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Author

F.-S. Lo; L.-Y. Chang; M.-H. Yang; Y.-H. Van; Y.-Y. Wai

Publisher

Walter de Gruyter GmbH

Published

2004

Language

EN

Field

Medicine (Health Sciences)