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Amniotic Fluid Volume in Intra-amniotic Inflammation with and Without Culture-proven Amniotic Fluid Infection in Preterm Premature Rupture of Membranes by Si Eun Lee; Roberto Romero; Seung Mi Lee; Bo Hyun Yoon is a Medicine article available to read on EtoBox.

What is Amniotic Fluid Volume in Intra-amniotic Inflammation with and Without Culture-proven Amniotic Fluid Infection in Preterm Premature Rupture of Membranes about?

## Objective: Previous studies reported that the clinical significance of intra-amniotic inflammation with a negative amniotic fluid (af) culture is similar to that of intra-amniotic inflammation with microbiologically-proven af infection. however, the magnitude of the fetal inflammatory response in these two conditions is different as gauged by umbilical cord c-reactive protein (crp) concentrations. we undertook this study to determine if the frequency of oligohydramnios is different in these two conditions. ## Methods: The amniotic fluid index (afi) was measured in 205 patients with preterm premature rupture of membranes (prom) (23 ng/ml). patients were divided into three groups according to the results of af culture and the presence or absence of intra-amniotic inflammation: 1) without intra-amniotic inflammation and a negative culture (n=109); 2) with intra-amniotic inflammation and a negative culture (n=44); and 3) a positive culture (n=52). ## Results: Patients with a positive culture had a higher frequency of oligohydramnios and a lower median afi than those with a negative culture but with intra-amniotic inflammation (p 0.1). ## Conclusion: Oligohydramnios was more frequent

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Author

Si Eun Lee; Roberto Romero; Seung Mi Lee; Bo Hyun Yoon

Publisher

Walter de Gruyter GmbH

Published

2010

Language

EN

Field

Medicine (Health Sciences)