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An MR-based technique for quantifying the deformation of articular cartilage during mechanical loading in an intact cadaver joint by Christoph Herberhold; Tobias Stammberger; Sonja Faber; Reinhard Putz; Karl-Hans Englmeier; Maximilian Reiser; Dr. med. Felix Eckstein is a Medicine article available to read on EtoBox.
What is An MR-based technique for quantifying the deformation of articular cartilage during mechanical loading in an intact cadaver joint about?
## Abstract The objective of this study was to develop an MR‐based technique for quantifying the deformation of articular cartilage during mechanical loading in an intact cadaver joint at high spatial and temporal resolution. A nonmetallic pressure device was constructed for applying loads of >1000 N to a femoro‐patellar articulation within an extremity coil of a clinical 1.5 T MRI scanner. Digital image processing methods were used to determine the location‐ and time‐dependent cartilage deformation in consecutive 2D fat‐suppressed FLASH images. Additionally, three‐dimensional reconstruction of the cartilage was performed from 3D fat‐suppressed FLASH image data. During the first 10 min of static compression, thickness changes between 10 and 30% were observed. Thickness changes greater than 50% and volume changes of 20% were recorded after 3 h. The technique permits analysis of the load and time‐dependent mechanical behavior of articular cartilage in its natural environment.
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- Author
- Christoph Herberhold; Tobias Stammberger; Sonja Faber; Reinhard Putz; Karl-Hans Englmeier; Maximilian Reiser; Dr. med. Felix Eckstein
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0740-3194)
- Published
- 1998
- Language
- EN
- Field
- Medicine (Health Sciences)