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Current Evidence for Pharmacological Management of Pediatric Concussion: a Systematic Review by Damla Hanalioglu; Sahin Hanalioglu; Jorge I. Arango; P. David Adelson is a Medicine article available to read on EtoBox.

What is Current Evidence for Pharmacological Management of Pediatric Concussion: a Systematic Review about?

Purpose Mild traumatic brain injury (mTBI) is a global public health problem and its current management is limited to rest and symptom management. Despite frequent use of drugs for symptom control, there is a lack of consensus on the optimal pharmacological management of post-concussive symptoms. We reviewed the relevant literature to compile the evidence about the pharmaceutical management of pediatric mTBI. Methods We performed a systematic review of the literature available in PubMed, Cochrane CENTRAL, and ClinicalTrials. Gov as well as through citation tracing. A modified PICO framework was used for the construction of search strategy and eligibility criteria. Risk of bias was assessed using RoB-2 tool for randomized and ROBINS-I for non-randomized studies. Results A total of 6260 articles were screened for eligibility. After exclusions, a total of 88 articles received full text review. A total of 15 reports representing 13 studies (5 randomized clinical trials, 1 prospective randomized cohort study, 1 prospective cohort study, and 6 retrospective cohort studies) met the eligibility criteria and were included in the review. We identified 16 pharmacological interventions in a to

Who reads Current Evidence for Pharmacological Management of Pediatric Concussion: a Systematic Review?

Author

Damla Hanalioglu; Sahin Hanalioglu; Jorge I. Arango; P. David Adelson

Publisher

Springer Science and Business Media LLC

Published

2023

Language

EN

Field

Medicine (Health Sciences)