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Can I read Fatty Acids and Eicosanoids Change during High-Fiber Diet in NAFLD Patients—Randomized Control Trials (RCT) on EtoBox?
Fatty Acids and Eicosanoids Change during High-Fiber Diet in NAFLD Patients—Randomized Control Trials (RCT) by Dominika Maciejewska-Markiewicz; Arleta Drozd; Joanna Palma; Karina Ryterska; Viktoria Hawryłkowicz; Patrycja Załęska; Ewa Wunsh; Katarzyna Kozłowska-Petriczko; Ewa Stachowska is a Medicine article available to read on EtoBox.
What is Fatty Acids and Eicosanoids Change during High-Fiber Diet in NAFLD Patients—Randomized Control Trials (RCT) about?
## Background: Non-alcoholic fatty liver disease (nafld) is a wide spectrum condition characterized by excessive liver fat accumulation in people who do not abuse alcohol. there is no effective medical treatment for nafld; therefore, most important recommendations to reduce liver steatosis are diet and lifestyle, including proper physical activity. the aim of our study was to analyze the fatty acids and eicosanoids changes in the serum of patients who consumed high-fiber rolls for 8 weeks. ## Materials and methods: The group of 28 caucasian participants was randomly divided into two groups, those who received 24 g of fiber/day-from 2 buns of 12 g each (n = 14), and those who received 12 g of fiber/day-from 2 buns of 6 g (n = 14). at the beginning and on the last visit of the 8-week intervention, all patients underwent nafld evaluation, biochemical parameter measurements, and fatty acids and eicosanoids evaluation. ## Results: Patients who received 12 g of fiber had significantly reduced liver steatosis and body mass index. in the group who received 24 g of fiber/day, we observed a trend to liver steatosis reduction ( = 0.07) and significant decrease in aspartate aminotransferase (
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- Author
- Dominika Maciejewska-Markiewicz; Arleta Drozd; Joanna Palma; Karina Ryterska; Viktoria Hawryłkowicz; Patrycja Załęska; Ewa Wunsh; Katarzyna Kozłowska-Petriczko; Ewa Stachowska
- Publisher
- MDPI AG
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)