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What is Opioid-Induced Hyperalgesia Post-Surgery about?
This systematic review and meta-analysis examined whether high doses of intraoperative opioids are associated with increased postoperative pain in patients undergoing surgery. Twenty-seven randomized controlled trials involving 1494 patients were included. The analysis found that patients receiving high intraoperative doses of opioids, particularly remifentanil, reported higher pain intensity scores at 1, 4, and 24 hours postoperatively and required more postoperative morphine over 24 hours compared to pati
- Author
- Natalia Santacruz
- Language
- EN