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Salivary Beta-endorphin in Nonsuicidal Self-injury: an Ambulatory Assessment Study by Lisa M. Störkel; Alexander Karabatsiakis; Johanna Hepp; Iris-Tatjana Kolassa; Christian Schmahl; Inga Niedtfeld is a Neuroscience article available to read on EtoBox.

What is Salivary Beta-endorphin in Nonsuicidal Self-injury: an Ambulatory Assessment Study about?

Nonsuicidal self-injury (NSSI) is a prevalent and impairing behavior, affecting individuals with and without additional psychopathology. To shed further light on biological processes that precede and result from NSSI acts, we built on previous cross-sectional evidence suggesting that the endogenous opioid system, and especially β-endorphin, is involved in the psychopathology of NSSI. This is the first study assessing salivary β-endorphin in daily life in the context of NSSI acts. Fifty-one female adults with repetitive NSSI participated over a period of 15 days in an ambulatory assessment study. Salivary β-endorphin was assessed before and after engagement in NSSI, during high urge for NSSI, and on a non-NSSI day. Furthermore, NSSI specific variables such as pain ratings, as well as method, severity, and function of NSSI were assessed. We found that β-endorphin levels immediately before an NSSI act were significantly lower than directly after NSSI. However, there was no difference between β-endorphin during high urge for NSSI and post NSSI measures. We found a positive association between severity of the self-inflicted injury and β-endorphin levels, but no significant association b

Who reads Salivary Beta-endorphin in Nonsuicidal Self-injury: an Ambulatory Assessment Study?

Author

Lisa M. Störkel; Alexander Karabatsiakis; Johanna Hepp; Iris-Tatjana Kolassa; Christian Schmahl; Inga Niedtfeld

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Neuroscience (Life Sciences)