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This study investigates the role of the blood-brain barrier (BBB) and edema in electrolyte-induced demyelination (EID) in rats, particularly focusing on the effects of hypertonic saline injection following a period of hyponatremia. It documents alterations in the BBB, including increased pinocytotic activity and focal interendothelial gaps, which contribute to cerebral edema. The findings suggest that rapid correction of hyponatremia leads to significant changes in brain water content and BBB integrity, imp

Author

tallapallysahith

Language

EN