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Elevated tacrolimus trough levels in association with mycophenolate mofetil‐induced diarrhea: A case report by M. Frühwirth; H. Fischer; B. Simma; H. Ellemunter is a Medicine article available to read on EtoBox.
What is Elevated tacrolimus trough levels in association with mycophenolate mofetil‐induced diarrhea: A case report about?
**Abstract:** The combination of tacrolimus (TAC) and mycophenolate mofetil (MMF) is frequently used for immunosuppression after organ transplantation (Tx), but the pharmacokinetics and interactions between the two drugs are poorly elucidated. We describe here the increase of TAC trough levels during MMF‐induced diarrhea in a 8‐yr‐old boy after kidney Tx. Early dose reduction of TAC, together with short‐term monitoring of TAC trough levels in the presence of diarrhea, is recommended.
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It is typically read by researchers, students, and practitioners in Medicine.
- Author
- M. Frühwirth; H. Fischer; B. Simma; H. Ellemunter
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley; Research Square (ISSN 1397-3142)
- Published
- 2001
- Language
- EN
- Field
- Medicine (Health Sciences)