Can I read Phenothiazines on EtoBox?

Phenothiazines by Jeanna M. Marraffa is a book available to read on EtoBox.

What is Phenothiazines about?

Phenothiazines are neuroleptic agents that affect a variety of receptors including dopaminergic receptor sites. Phenothiazine, the parent chemical of a variety of different phenothiazine-based therapeutics, has been used extensively as an insecticide, fungicide, antibacterial and anthelminthic agent before being used for certain psychiatric conditions (Mitchell, 1994). Phenothiazines, in humans, are used most commonly to treat psychosis including schizophrenia; violent, agitated, disturbed behavior; and mania secondary to of bipolar disorder. Certain phenothiazines are also used for their antiemetic effects. There are different types of phenothiazines, based on the chemical structure including aliphatic compounds such as chlorpromazine, piperidine based compounds such as thioridazine, and piperazine based compounds such as prochlorperazine. Phenothiazines primarily block postsynaptic neurotransmission by binding to dopamine (D1 and D2), muscarinic, histamine H1, and serotonergic 5-HT2 receptors. Phenothiazines also possess peripheral alpha-adrenergic receptor blockade and quinidine-like cardiac effects. Phenothiazines may lower the seizure threshold. Clinical signs of toxicity from

Author

Jeanna M. Marraffa

Publisher

Elsevier Science & Technology Books

Published

2024

Language

EN

ISBN

9780323854344

Subjects

Medical, Medicine