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Mortality and prognostic factors in patients with bullous pemphigoid: a retrospective multicenter Italian study by F. Bardazzi; F. Filippi; M.A. Chessa; M. Iommi; C. Loi; A. Campanati; G. Rizzetto; C. Tagliati; L. Atzori; S. Muratori; G. Genovese; P. Gisondi; D. Schena; R. Balestri; G. Rech; C. Feliciani; C. Lasagni; L. Bigi; C. De Simone; G. Di Zenzo; F. Moro; A. Borghi; V. Di Lernia; G. D'Arrigo; G. Tripepi; M. Gori; A. Pitino is a Medicine article available to read on EtoBox.
What is Mortality and prognostic factors in patients with bullous pemphigoid: a retrospective multicenter Italian study about?
## Abstract ## Introduction Bullous pemphigoid is the most common autoimmune bullous dermatosis. In recent years several studies have tried to identify the main factors of the disease related with an increased risk of death. The aim of this multicenter Italian study was to assess the risk score of death considering epidemiologic, clinical, immunological, and therapeutic factors in a cohort of patients affected by bullous pemphigoid and try to identify the cumulative survival up to 120 months. ## Methods We retrospectively reviewed the medical records of patients with bullous pemphigoid who were diagnosed between 2005 and 2020 in the 12 Italian centers. Data collected included sex, age at the time of diagnosis, laboratory findings, severity of disease, time at death/censoring, treatment, and multimorbidity. ## Results A total of 572 patients were included in the study. The crude mortality rate was 20.6%, with an incidence mortality rate of 5.9 × 100 person/year. The mortality rate at 1, 3, 5, and 10 years was 3.2%, 18.2%, 27.4% and 51.9%, respectively. Multivariate model results showed that the risk of death was significantly higher in patients older than 78 years, in presence of mu
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- Author
- F. Bardazzi; F. Filippi; M.A. Chessa; M. Iommi; C. Loi; A. Campanati; G. Rizzetto; C. Tagliati; L. Atzori; S. Muratori; G. Genovese; P. Gisondi; D. Schena; R. Balestri; G. Rech; C. Feliciani; C. Lasagni; L. Bigi; C. De Simone; G. Di Zenzo; F. Moro; A. Borghi; V. Di Lernia; G. D'Arrigo; G. Tripepi; M. Gori; A. Pitino
- Publisher
- Wiley
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)