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What is Isosteres and Bioisosteres in Chemistry about?

Bioisosteres are structurally dissimilar groups or substituents that produce broadly similar biological properties to another structure. The document lists various examples of bioisosteres including: 1. Univalent, bivalent, trivalent, and tetravalent atom replacements such as -CH3 = -NH2, -CH2- = -NH-, and -CH= = -N=. 2. Ring structure equivalents like nitrogen-containing rings. 3. Functional group replacements like -H = -F, carbonyl = nitrile, and carboxylic acid = sulfonamide or phosphonamide. 4. Oth

Author

jfsantamariame

Language

EN