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Can I read Functional Relationship between Osteogenesis and Angiogenesis in Tissue Regeneration on EtoBox?
Functional Relationship between Osteogenesis and Angiogenesis in Tissue Regeneration by Francesca Diomede; Guya Diletta Marconi; Luigia Fonticoli; Jacopo Pizzicanella; Ilaria Merciaro; Placido Bramanti; Emanuela Mazzon; Oriana Trubiani is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Functional Relationship between Osteogenesis and Angiogenesis in Tissue Regeneration about?
Bone tissue renewal can be outlined as a complicated mechanism centered on the interaction between osteogenic and angiogenic events capable of leading to bone formation and tissue renovation. The achievement or debacle of bone regeneration is focused on the primary role of vascularization occurrence; in particular, the turning point is the opportunity to vascularize the bulk scaffolds, in order to deliver enough nutrients, growth factors, minerals and oxygen for tissue restoration. The optimal scaffolds should ensure the development of vascular networks to warrant a positive suitable microenvironment for tissue engineering and renewal. Vascular Endothelial Growth Factor (VEGF), a main player in angiogenesis, is capable of provoking the migration and proliferation of endothelial cells and indirectly stimulating osteogenesis, through the regulation of the osteogenic growth factors released and through paracrine signaling. For this reason, we concentrated our attention on two principal groups involved in the renewal of bone tissue defects: the cells and the scaffold that should guarantee an effective vascularization process. The application of Mesenchymal Stem Cells (MSCs), an excelle
Who reads Functional Relationship between Osteogenesis and Angiogenesis in Tissue Regeneration?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Francesca Diomede; Guya Diletta Marconi; Luigia Fonticoli; Jacopo Pizzicanella; Ilaria Merciaro; Placido Bramanti; Emanuela Mazzon; Oriana Trubiani
- Publisher
- MDPI AG
- Published
- 2020
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)