About this Materials Science article
Brilliant glycans and glycosylation: Seq and ye shall find by Guanwen Gao; Chen Li; Wenguo Fan; Mingtao Zhang; Xinming Li; Wenqing Chen; Weiquan Li; Runzhang Liang; Zesong Li; Xiao Zhu is a Materials Science article available to read on EtoBox.
Proteoglycosylation is the addition of monosaccharides or glycans to the protein peptide chain. This is a common post-translational modification of proteins with a variety of biological functions. At present, more than half of all biopharmaceuticals in clinic are modified by glycosylation. Most glycoproteins are potential drug targets and biomarkers for disease diagnosis. Therefore, in-depth study of glycan structure of glycoproteins will ultimately improve the sensitivity and specificity of glycoproteins for clinical disease detection. With the deepening of research, the function and application value of glycans and glycosylation has gradually emerged. This review systematically introduces the latest research progress of glycans and glycosylation. It encompasses six cancers, four viruses, and their latest discoveries in Alzheimer's disease, allergic diseases, congenital diseases, gastrointestinal diseases, inflammation, and aging.
It is typically read by researchers, students, and practitioners in Materials Science.
- Author
- Guanwen Gao; Chen Li; Wenguo Fan; Mingtao Zhang; Xinming Li; Wenqing Chen; Weiquan Li; Runzhang Liang; Zesong Li; Xiao Zhu
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Materials Science (Physical Sciences)