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Intracranial Hemorrhage Progressing to Porencephaly as a Result of Congenitally Acquired Cytomegalovirus Infection—an Illustrative Report by Asif Moinuddin; Robert C. McKinstry; Kimberly A. Martin; Jeffrey J. Neil is a Medicine article available to read on EtoBox.

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## Abstract ## Objective To report ultrasound and magnetic resonance imaging (MRI) findings in a fetus with intracranial hemorrhage and porencephaly, presumed secondary to intrauterine cytomegalovirus (CMV) infection. ## Methods A 20‐year‐old, G2, P1 woman presented at 28.6 weeks' gestation after ultrasound examination demonstrated apparently isolated fetal ascites. Evaluation included maternal serology, amniocentesis, and repeated ultrasound examinations. Fetal MRI evaluation was also performed. The infant was born at 35 weeks' gestational age. ## Results Maternal serology was positive for CMV IgG. Intrauterine CMV infection was confirmed using polymerase chain reaction (PCR). At 31.6 weeks' gestation, ultrasound demonstrated borderline lateral cerebral ventriculomegaly. MRI of the fetal brain on the same day demonstrated parenchymal hemorrhage in the right posterior temporal and parietal regions along with mild ventricular enlargement. Sonography one day before delivery revealed brain parenchymal cystic change consistent with porencephaly of the right posterior temporal and parietal region. Postnatal ultrasound, computed tomography (CT), and MRI confirmed the diagnosis of a poren

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Author

Asif Moinuddin; Robert C. McKinstry; Kimberly A. Martin; Jeffrey J. Neil

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0197-3851)

Published

2003

Language

EN

Field

Medicine (Health Sciences)