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This document discusses recent advances in developing complex in vitro models of human skeletal muscle beyond traditional monolayer cell cultures. It focuses on models involving skeletal myogenic differentiation from human primary myoblasts, immortalized myoblast cell lines, or pluripotent stem cells, often supported by 3D scaffolding. These advanced models aim to better mimic the physiological complexity and hierarchical organization of native human skeletal muscle tissue to enable more clinically relevant

Author

metrorespo

Language

EN