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Can I read Regioselective synthesis of optically active (pyrazolyl)pyridines with adjacent quaternary carbon stereocenter: chiral N,N-donating ligands on EtoBox?
Regioselective synthesis of optically active (pyrazolyl)pyridines with adjacent quaternary carbon stereocenter: chiral N,N-donating ligands by Rafał Kowalczyk; Jacek Skarżewski is a Chemistry article available to read on EtoBox.
What is Regioselective synthesis of optically active (pyrazolyl)pyridines with adjacent quaternary carbon stereocenter: chiral N,N-donating ligands about?
Novel optically active 2-(pyrazol-1-yl)pyridines have been prepared using resolved the O-methyl ether of atrolactic acid as a source of the adjacent quaternary carbon stereocenter. Different regioisomers were formed selectively in the reaction of 2-hydrazinopyridines with the chiral 1,3-diketone and in the nucleophilic substitution of 2-chloropyridines with the potassium salt of the chiral pyrazole. The second route gave 2-(pyrazol-1-yl)pyridines with the stereogenic center neighboring the coordinating nitrogen in the pyrazole ring. Also, new C 2 -symmetric chiral ligands based on 2,6-bis(pyrazolyl)pyridine and 6,6 0 -bis(pirazolyl)-2,2 0 -bipyridine structures were obtained.
Who reads Regioselective synthesis of optically active (pyrazolyl)pyridines with adjacent quaternary carbon stereocenter: chiral N,N-donating ligands?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Rafał Kowalczyk; Jacek Skarżewski
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0040-4020)
- Published
- 2005
- Language
- EN
- Field
- Chemistry (Physical Sciences)