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A brief history of brain iron accumulation in Parkinson disease and related disorders by Paul B. Foley; Dominic J. Hare; Kay L. Double is a Neuroscience article available to read on EtoBox.

What is A brief history of brain iron accumulation in Parkinson disease and related disorders about?

Iron has a long and storied history in Parkinson disease and related disorders. This essential micronutrient is critical for normal brain function, but abnormal brain iron accumulation has been associated with extrapyramidal disease for a century. Precisely why, how, and when iron is implicated in neuronal death remains the subject of investigation. In this article, we review the history of iron in movement disorders, from the first observations in the early twentieth century to recent efforts that view extrapyramidal iron as a novel therapeutic target and diagnostic indicator.

Who reads A brief history of brain iron accumulation in Parkinson disease and related disorders?

Author

Paul B. Foley; Dominic J. Hare; Kay L. Double

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Neuroscience (Life Sciences)