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This study evaluates the 5-year clinical outcomes of kidney transplant recipients who underwent desensitization with imlifidase, an IgG-cleaving enzyme, prior to incompatible transplantation. Out of 8 participants, 7 were alive at 5 years, with some experiencing donor-specific antibody (DSA) rebound, but generally lower antibody strength compared to pre-treatment levels, and no significant increase in major infections. The findings suggest favorable long-term outcomes for imlifidase-enabled transplants, des
- Author
- MARIA LEIVA
- Language
- EN