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What is Erythromycin Nanosuspension Formulation about?

The document describes research into formulating nanosuspensions of erythromycin stearate to improve its bioavailability. Nanosuspensions were prepared using high pressure homogenization with various drug to surfactant ratios, stirring speeds, and times. The optimized formulation used a 1:2:2 ratio of drug to poloxamer 188 to tween 20, stirred at 25,000 rpm for 25 minutes, then lyophilized. This formulation was evaluated and found stable with the drug compatible with excipients. Nanosuspensions improved dis

Author

Ddaniati Bougenville L

Language

EN