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Effectiveness of Emergency versus Nonemergent Coronary Angiography After Out-of-Hospital Cardiac Arrest without ST-Segment Elevation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Aqsa Shoaib; Najwa Salim; Abdul Rehman Shahid; Muhammad Ali Amir; Moeez Ibrahim Shiraz; Aliza Ayaz; Bilal Shahid Khan; Saad Ali Ansari; Mahammed Khan Suheb; Nooraldin Merza; Izza Shahid is a Medicine article available to read on EtoBox.

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The optimal timing of coronary angiography (CAG) in patients after out-of-hospital cardiac arrest (OHCA) without ST-segment elevation remains controversial. Therefore, we conducted a meta-analysis of randomized control trials to investigate the effectiveness of emergency CAG versus delayed CAG in OHCA patients with a non-ST-segment elevated rhythm. PubMed, Scopus, CINAHL, Cochrane CENTRAL, and JBI databases were searched from inception to September 7, 2022. Our primary end point was survival with a good neurological outcome, whereas the secondary outcomes included short-term survival, mid-term survival, recurrent arrhythmias, myocardial infarction after hospitalization, major bleeding, acute kidney injury, and left ventricular ejection fraction. Nine randomized control trials involving 2,569 patients were included in this analysis. Our meta-analysis showed no significant difference in the improvement of neurological outcome (RR 0.96, 95% Confidence Interval [CI] [0.87, 1.06]), short-term survival (risk ratio [RR] 0.98, 95% CI [0.89, 1.08]), mid-term survival (RR 0.98, 95% CI [0.87, 1.10]), recurrent arrhythmias (RR 1.02, 95% CI [0.50, 2.06]), myocardial infarction (RR 0.66, 95% CI

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Author

Aqsa Shoaib; Najwa Salim; Abdul Rehman Shahid; Muhammad Ali Amir; Moeez Ibrahim Shiraz; Aliza Ayaz; Bilal Shahid Khan; Saad Ali Ansari; Mahammed Khan Suheb; Nooraldin Merza; Izza Shahid

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Medicine (Health Sciences)