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Can I read Ischemic brain injury and cell calcium: Morphologic and therapeutic aspects on EtoBox?
Ischemic brain injury and cell calcium: Morphologic and therapeutic aspects by Jos Van Reempts; Marcel Borgers is a Medicine article available to read on EtoBox.
What is Ischemic brain injury and cell calcium: Morphologic and therapeutic aspects about?
Histopathological data obtained from different experimental models of hypoxia and ischemia were evaluated in order to extend current knowledge of mechanisms responsible for delayed neuronal cell death. Special attention is given to the distribution of calcium (Ca2+) in vulnerable areas during the postischemic period. Between an initial defensive Ca2+ sequestration, which is completely reversible, and final toxic Ca2+ overload, which is associated with irreversible neuronal necrosis, important Ca2+ shifts could be demonstrated cytochemically. Such shifts occur mainly at excitatory presynaptic sites and seem to precede structural ischemic cell change in postsynaptic areas. Recent results obtained with some Ca2+ entry blockers indicate that prophylactic treatment and postischemic intervention prevent cytosolic Ca2+ overload and reduce delayed brain injury.
Who reads Ischemic brain injury and cell calcium: Morphologic and therapeutic aspects?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Jos Van Reempts; Marcel Borgers
- Publisher
- Elsevier Science; Elsevier ; Mosby Inc.; Elsevier BV (ISSN 1097-6760)
- Published
- 1985
- Language
- EN
- Field
- Medicine (Health Sciences)