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Circadian Abnormalities in Older Adults by Shawn D. Youngstedt; Daniel F. Kripke; Jeffrey A. Elliott; Melville R. Klauber is a Neuroscience article available to read on EtoBox.

What is Circadian Abnormalities in Older Adults about?

This study examined the circadian phase adjustment of symptomatic elders ages 60–79 years in comparison with that of young, healthy adults ages 20–40 years. Seventy‐two elders with complaints of insomnia or depression, and 30 young, healthy adults were assessed for 5–7 days at home. Sleep and illumination were recorded with Actillume wrist monitors and sleep diaries. Urine was collected over two 24‐hr periods and assayed for 6‐sulphatoxymelatonin (6‐smt). The volunteers were then observed continuously for 5 nights and 4 days in the laboratory. In the laboratory, sleep periods were fixed at 8 hr with polysomnographic assessment of sleep, apnea‐hypopnea, and nocturnal myoclonus. Circadian dispersion, defined as the mean variation of 6‐smt acrophase from the median age‐specific acrophase, was significantly greater in the older vs. young adults. Likewise, circadian malsynchronization, defined as the absolute number of hours (advance or delay) between the 6‐smt acrophase and the middle of the sleep period, was significantly greater in the older vs. young volunteers. For the older volunteers, multiple regressions were calculated associating sleep with potential correlates of sleep distur

Who reads Circadian Abnormalities in Older Adults?

Author

Shawn D. Youngstedt; Daniel F. Kripke; Jeffrey A. Elliott; Melville R. Klauber

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0742-3098)

Published

2001

Language

EN

Field

Neuroscience (Life Sciences)