Can I read Polymyxin Antibiotics: From Laboratory Bench to Bedside (Advances in Experimental Medicine and Biology, 1145) on EtoBox?

Polymyxin Antibiotics: From Laboratory Bench to Bedside (Advances in Experimental Medicine and Biology, 1145) by Jian Li, (Pharmacologist); Roger L Nation; Keith S Kaye is a nonfiction available to read on EtoBox.

What is Polymyxin Antibiotics: From Laboratory Bench to Bedside (Advances in Experimental Medicine and Biology, 1145) about?

This volume is the first-ever complete treatise on polymyxins and presents the most comprehensive and up-to-date reviews of all major research and clinical topics from chemistry, microbiology, pharmacology, clinical use, to drug discovery. All chapters were written by internationally leading researchers and clinicians in the field. It is our wish that readers discover the importance of polymyxin structure in relation to the mechanisms of activity, resistance and toxicity. We emphasized that reliable analytic methods for polymyxins are critical when investigating their pharmacokinetics (PK) and pharmacodynamics (PD). The complicated dose definitions and different pharmacopoeial standards have already compromised the safe use of polymyxins in patients. Therefore, informed by the latest pharmacological information, scientifically-based dosing recommendations have been proposed for intravenous polymyxins. Considering the PK/PD limitations and potential development of resistance, polymyxin combinations are encouraged; however, the current literature has not shown definite microbiological benefits, possibly because most clinical studies to date overlooked key PK/PD principles. Nephrotoxi

Who reads Polymyxin Antibiotics: From Laboratory Bench to Bedside (Advances in Experimental Medicine and Biology, 1145)?

Author

Jian Li, (Pharmacologist); Roger L Nation; Keith S Kaye

Publisher

Springer International Publishing Imprint, Springer

Published

2019

Language

EN

ISBN

9783030163716

Category

nonfiction

Subjects

Science, Medical, Biology