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What is GLUT1 Promotes Cell Proliferation Via Binds and Stabilizes Phosphorylated EGFR in Lung Adenocarcinoma about?

The study investigates the role of GLUT1 in promoting cell proliferation in lung adenocarcinoma (LUAD) through its interaction with phosphorylated EGFR, which enhances tumor progression. High GLUT1 expression correlates with poor patient survival, and its knockdown reduces cell proliferation, migration, and invasion while inducing apoptosis. The findings suggest that combining GLUT1 inhibitors with EGFR-tyrosine kinase inhibitors may offer a novel therapeutic strategy for LUAD treatment.

Author

celebubudiaz

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EN