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1) The study examined whether inhibiting Rho-kinase (Y-27632) could reduce caspase-3 activity in retinal ganglion cells (RGCs) of juvenile mice injected with sodium hyaluronate. 2) Mice were injected with sodium hyaluronate and then treated with Y-27632 at concentrations of 1μM, 10μM, and 100μM. 3) Results showed a significant negative correlation between caspase-3 activity in RGCs and Y-27632 concentration, indicating Y-27632 inhibits caspase-3 activity in a dose-dependent manner.

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