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Long-term Exposure to Ambient Air Pollutants and Age-related Macular Degeneration in Middle-aged and Older Adults by Min Jae Ju; Junghoon Kim; Sung Kyun Park; Dong Hyun Kim; Yoon-Hyeong Choi is a Environmental Science article available to read on EtoBox.

What is Long-term Exposure to Ambient Air Pollutants and Age-related Macular Degeneration in Middle-aged and Older Adults about?

In developed countries, age-related macular degeneration (AMD) is a leading cause of irreversible blindness in adults. The key pathways of AMD are suggested to be excessive oxidative stress and inflammation in the central retina. Because air pollution has been found capable of inducing oxidative stress and inflammation, it may play a role in development of AMD. This study investigated the association between ambient air pollution and AMD in 15,115 middle-aged and older adults (≥40 years) from Korean National Health and Nutrition Examination Survey 2008-2012. After controlling for important confounders, ambient NO 2 and CO in current-to-5 prior years and PM 10 in 2-to-5 prior years were significantly associated with higher prevalence of early AMD, while O 3 in current-to-5 prior years was significantly associated with lower prevalence of early AMD. When modeled air pollution within administrative division units, its ORs with an IQR increase in NO 2 , CO, and O 3 at current year were 1.24 (95% CI: 1.05-1.46), 1.22 (95% CI: 1.09-1.38), and 0.80 (95% CI: 0.70-0.92), respectively. Overall, results from air pollution at local/town units were consistent with those at administrative divisi

Who reads Long-term Exposure to Ambient Air Pollutants and Age-related Macular Degeneration in Middle-aged and Older Adults?

Author

Min Jae Ju; Junghoon Kim; Sung Kyun Park; Dong Hyun Kim; Yoon-Hyeong Choi

Publisher

Elsevier BV

Published

2022

Language

EN

Field

Environmental Science (Physical Sciences)