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Cutoff point estimation for serum vitamin D concentrations to predict cardiometabolic risk in Brazilian children by Luana Cupertino Milagres; Mariana De Santis Filgueiras; Naruna Pereira Rocha; Lara Gomes Suhett; Fernanda Martins de Albuquerque; Leidjaira Lopes Juvanhol; Sylvia do Carmo Castro Franceschini; Juliana Farias de Novaes is a Medicine article available to read on EtoBox.

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## Background/objectives: To evaluate serum 25(oh)d concentrations and determine a cutoff point for cardiometabolic risk in children. ## Subject/methods: This is a cross-sectional study with a representative sample of 378 8-9-year-old children from all urban schools in the city of viçosa, mg, brazil. sociodemographic data and information on lifestyle, and food consumption were collected. biochemical evaluation included glucose, triglycerides, leptin, calcidiol [25(oh)d], and parathormone. body composition was assessed by dual energy x-ray absorptiometry. cardiometabolic risk was considered when nontraditional risk markers were detected, including triglyceride × glycemia index (tyg index), hyperleptinemia, and hypertriglyceridemic waist phenotype (hwp). the receiver operating characteristic curve (roc) was used to define the cutoff point for serum 25(oh)d to predict cardiometabolic risk. ## Results: 25(oh)d showed better predictive capacity for grouping of cardiometabolic risk markers than for either single or paired markers. the area under the curve for grouping of risk markers was 0.636 (95% ci: 0.585, 0.685, p < 0.001). the cutoff point to predict cardiometabolic risk was defined

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Author

Luana Cupertino Milagres; Mariana De Santis Filgueiras; Naruna Pereira Rocha; Lara Gomes Suhett; Fernanda Martins de Albuquerque; Leidjaira Lopes Juvanhol; Sylvia do Carmo Castro Franceschini; Juliana Farias de Novaes

Publisher

Nature Publishing Group; Springer Science and Business Media LLC (ISSN 0954-3007)

Published

2020

Language

EN

Field

Medicine (Health Sciences)