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The study investigates the effects of tau ablation in excitatory neurons on epilepsy, sudden unexpected death in epilepsy (SUDEP), and autism behaviors in a Dravet syndrome mouse model. Results show that reducing tau in excitatory neurons significantly decreases seizure activity, SUDEP, and autism-like behaviors, while tau ablation in inhibitory neurons does not yield similar benefits. This suggests that targeting tau reduction in excitatory neurons could be a therapeutic strategy for managing Dravet syndro
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- evalepinaypro
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- EN