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Protein Templated Synthesis of Dinucleotide Repeat DNA by An Antiphage Reverse Transcriptase by lynnlollman is a document available to read on EtoBox.
The study investigates the protein-templated synthesis of dinucleotide repeat DNA by the bacterial defense-associated reverse transcriptase DRT3, which consists of two distinct reverse transcriptases and a noncoding RNA. DRT3 synthesizes alternating poly(GT/AC) double-stranded DNA using a unique mechanism that does not rely on a nucleic acid template, revealing new insights into nucleic acid polymerization. Cryo-electron microscopy structures provide detailed insights into the assembly and function of the D
- Author
- lynnlollman
- Language
- EN