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Efficient new methods for oxidation are always welcome. The Dess-Martin periodinane has become the workhorse for alcohol to aldehyde or ketone conversion in organic research labs around the world. Viktor V. Zhdankin of the University of Minnesota, Duluth has described (Chem. Commun. 2004, 106) a complementary family of reagents. Oxidation of an ester 1 of o-iodobenzoic acid with NaOCl delivers 2. Depending on the ester, the reagent 2 is soluble and an effective oxidant, with KBr catalysis, in a wide range of organic solvents. Presumably, the spent oxidant can be recovered and recycled. 1 y 2 Chromium-based oxidants, noteworthy for their specificity and ease of use, continue to be popular. Enayatollah Mottaghinejad of Azad University of Iran, Tehran has found (Tetrahedron Lett. 2004,45, 8823) that barium dichromate, easily prepared, smoothly oxidizes alcohols to aldehydes and ketones in refluxing acetonitrile. oO" = CH,CN 0"" 3 4 A recent report (J. Urg. Chem. 2004,69,8510) by Paul G. Williard of Brown University and Ruggero Curci of Universith di Bara of the oxidation of 5 to 6 serves as a timely reminder that the widely-used epoxidation reagent dimethyl dioxirane is also useful fo
- Author
- Taber, Douglass F.
- Publisher
- John Wiley & Sons, Incorporated
- Published
- 2006
- Language
- EN
- ISBN
- 9780470053317