Can I read Gestational transient hyperthyroxinaemia (GTH): screening for thyroid function in 23 163 pregnant women using dried blood spots on EtoBox?

Gestational transient hyperthyroxinaemia (GTH): screening for thyroid function in 23 163 pregnant women using dried blood spots by Shinichi Tanaka; Hideto Yamada; Emi H. Kato; Itsuko Furuta; Masaru Fukushi; Nobuo Takasugi; Seiichiro Fujimoto is a Medicine article available to read on EtoBox.

What is Gestational transient hyperthyroxinaemia (GTH): screening for thyroid function in 23 163 pregnant women using dried blood spots about?

## OBJECTIVE Transient elevation of serum free T4 (gestational transient hyperthyroxinaemia; GTH) occurs occasionally during normal pregnancy, especially in early gestation. However, the frequency of GTH and its clinical features remain unclear to date. The aim of this study was to determine the occurrence rate of GTH and the relation between serum levels of hCG, free T4 (fT4), and TSH in a large number of pregnant women. ## DESIGN The four criteria of GTH were as follows: (1) no past history of thyroid disease, (2) negative tests for MCHA and TGHA, (3) no multiple pregnancies or trophoblastic disease and (4) transient hyperthyroxinaemia at less than 16 weeks of gestation. Thyroid function and hCG levels in 23 163 pregnant women were evaluated by mass sreening. If individual fT4 levels were more than the upper limit, blood re‐sampling and the clinical and laboratory analysis of thyroid function were performed to exclude women with thyroid disease. The concentrations of hCG, fT4, and TSH in women with GTH and normal pregnant controls (__n__ = 218) were compared. Regression analysis was performed for the comparison between hCG, fT4, and TSH levels in women with GTH. ## MEASUREMENTS B

Who reads Gestational transient hyperthyroxinaemia (GTH): screening for thyroid function in 23 163 pregnant women using dried blood spots?

Author

Shinichi Tanaka; Hideto Yamada; Emi H. Kato; Itsuko Furuta; Masaru Fukushi; Nobuo Takasugi; Seiichiro Fujimoto

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley; Research Square (ISSN 0300-0664)

Published

1998

Field

Medicine (Health Sciences)