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This systematic review examines the role of astrocyte dysregulation in the pathogenesis of epilepsy, highlighting its multifactorial nature involving genetic, structural, and glial cell factors. The review synthesizes findings from 24 studies, revealing that astrocytic dysfunctions, such as impaired potassium buffering and disrupted glutamatergic transmission, contribute to increased neuronal excitability and seizure susceptibility. Ultimately, understanding these mechanisms is crucial for developing target

Author

Milon

Language

EN