Can I read Clinical Aspects of Risk in Women with Endometrial Carcinoma on EtoBox?

Clinical Aspects of Risk in Women with Endometrial Carcinoma by Thomas W. Burke; Wesley C. Fowler Jr.; C. Paul Morrow is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Clinical Aspects of Risk in Women with Endometrial Carcinoma about?

Carcinoma of the endometrium is the most common gynecologic malignancy, expected to account for 33,000 new cases and 6,000 deaths in 1995. Most endometrial cancers occur in postmenopausal women and produce abnormal vaginal bleeding. Some women exhibit the premalignant changes of atypical endometrial hyperplasia before developing an overt carcinoma. Identified epidemiologic risk factors include obesity, diabetes mellitus, use of unopposed exogenous estrogens, estrogen-secreting tumors, and a reproductive history characterized by prolonged estrogenic predominance. Diagnosis can be readily established by outpatient endometrial biopsy. Because clinical estimates of disease extent and spread are subject to substantial error, endometrial cancer is now a surgically staged neoplasm. A well-defined set of surgicopathologic risk factors have been incorporated into the staging scheme. Women with extrauterine disease comprise about 20% of cases and are at greatest risk for tumor recurrence and death from disease. Within the much larger group of women whose tumors are limited to the uterus, recurrence risk can be stratified by cytologic grade, cell type, depth of myometrial invasion, and extens

Who reads Clinical Aspects of Risk in Women with Endometrial Carcinoma?

Author

Thomas W. Burke; Wesley C. Fowler Jr.; C. Paul Morrow

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0730-2312)

Published

1995

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)