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Prognostic value of cardiac troponin I elevation after percutaneous coronary intervention in patients with chronic renal insufficiency: A 12-month outcome analysis by Luis Gruberg; Shmuel Fuchs; Ron Waksman; Augusto D. Pichard; Kenneth M. Kent; John R. Laird; Hongsheng Wu; Sayed Elsayyad; Craig M. Allen; Lowell F. Satler is a Medicine article available to read on EtoBox.

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## Abstract Serum cardiac troponin I (cTnI) is a highly specific marker for myocardial damage in patients with chronic renal insufficiency (CRI), unlike creatine kinase myocardial band fraction (CK‐MB), which may be elevated in the absence of myocardial injury in patients with CRI. We studied 116 consecutive CRI patients (serum creatinine ≥ 1.8 mg/dL, not on dialysis) with normal baseline cTnI levels who underwent successful percutaneous coronary intervention (PCI). Patients were divided into two groups: group 1, elevated postprocedural cTnI (n = 50), and group 2, normal cTnI (n = 66). Patients with elevated cTnI were older and had a higher incidence of postinfarction angina and lower creatinine clearance compared to patients who did not have cTnI elevation. Atheroablative devices (rotational and directional atherectomy and excimer laser coronary angioplasty) were more frequently used in group 1 patients (27.1% vs. 18.5%; __P__ = 0.04). In‐hospital mortality, cardiac mortality, and Q‐wave myocardial infarction rates did not differ between the two groups. At 12‐month follow‐up, total mortality rates were significantly higher in group 1 (28.0% vs. 9.9%; __P__ = 0.002). Multivariate a

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Author
Luis Gruberg; Shmuel Fuchs; Ron Waksman; Augusto D. Pichard; Kenneth M. Kent; John R. Laird; Hongsheng Wu; Sayed Elsayyad; Craig M. Allen; Lowell F. Satler
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1522-1946)
Published
2002
Language
EN
Field
Medicine (Health Sciences)